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Rapid turnaround pharmacokinetic studies

Ricerca's preclinical metabolism services give you the ADME, pharmacokinetic and metabolism profiling data you need to prepare for the IND and define a Phase I clinical study design.

 

We perform in vivo and in vitro, routine and non-routine, radiolabeled and non-labeled studies. Combining these capabilities with today's powerful new technologies we can also customize programs that identify the most promising compound from a candidate group.

 

Our in vivo studies determine the behavior of your development compound's pharmacokinetic parameters in animals, including metabolite profiling, disposition across tissues and organs, and structural identification of metabolites. In support of your study, Ricerca provides on-site radiolabel synthesis of your drug candidate.

 

Other services, such as metabolite standards synthesis and our broad range of on-site analytical expertise, mean you'll be able to choose better development candidates and fully evaluate them more quickly.