The Bicoll Group

Based in Munich, Germany and Shanghai, P.R. China, is a biopharmaceutical company offering products and services to accelerate all stages of the drug discovery process, from hit generation to lead optimization.

Bicoll provides a multi-disciplinary approach tailored to advance the clients’ drug discovery programs, combining experience and expertise in both high-tech natural product chemistry and medicinal chemistry.

Bicoll identifies active small molecules for drug discovery and related innovative fields. A major technological focus is set on making compounds from natural resources (plants) compatible with the clients’ screening systems. Bicoll’s advanced approach of property-based natural product libraries is able to rapidly select the best leads with superior drug-like profiles for further development. With subsequent medicinal chemistry and custom synthesis Bicoll provides seamless substantial services for the global pharmaceutical and biotech industries.

Joining forces with Ricerca’s Discovery group, Bicoll has assisted many clients in the areas of custom synthesis, compound libraries, and structure-activity relationship studies.

Latitude Pharmaceuticals, Inc.

A highly regarded and innovative formulation development boutique.  We have extensive experience creating ground-breaking formulation approaches for difficult APIs with potential commercialization showstoppers such as insolubility, instability, vein irritation, high dose and/or bulky volume, CNS toxicity, lacking a unique PK profile, or lacking IP protection. 
 
In an active partnership with Ricerca, Latitude’s formulation experts can develop a value-adding formulation to realize the maximum commercial potential of your project.  Our activities complement the drug discovery, process optimization, scale up, and animal model services of Ricerca, providing one-stop shopping convenience to our clients for their drug development needs.

Xcelience

Xcelience is a premier provider of formulation development and manufacturing solutions. From preformulation to clinical supplies manufacturing and stability, we have one focus: the success of your project.

Our state-of-the-art equipment, including the Xcelodose® 600 S, XRD, and TF-1 Blister Packaging Thermoformer, combined with our years of experience providing innovative solutions make the path from compound to clinic feel effortless. We are more than just a service.  We are formulation development made easy – at last.

Xpert Services

• Preformulation: Salt Screens, Polymorph Screens, Drug Substance Characterization, Excipient Compatibility, Accelerated Stability, Chiral Stability
• Formulation: Solids (tablets, capsules, sustained release and coatings), Semi-solids (ointments, creams, gels), Dispersed Systems (Emulsions, Suspensions), Liquids (Orals, Ophthalmics, Parenterals
• Analytical: Method Development, Qualification and Validation, Raw Materials Testing, Stability Sample Analysis, Dissolution Testing, Residual Solvent Analysis, Chiral Determination, Cleaning Evaluations, Technical Packages for Drug Substances
• Stability: ICH Conditions, Protocol Design, Report Generation, Sample Analysis, Secure Storage Area, 21CFR11 Compliant Laboratory Information System (SLIM)
• Clinical Trial Supplies Manufacturing, Packaging and Labeling: API into Capsule, Tablets and Capsules, Liquid in Capsule, Semi-Solids, Non-sterile Liquid, Reference Product Blinding, Packaging and Labeling Services, Creation of Matching Placebo, Creation and Qualification of Blinded Reference Product, Process Qualification, Process Definition Optimization, and Technology Transfer.