Metabolic/Endocrine

Endocrine disorders involve the body’s over- or under-production of certain hormones, while metabolic disorders affect the body’s ability to process certain nutrients and vitamins. Endocrine disorders include hypothyroidism, diabetes, diseases of the adrenal glands and ovarian dysfunction among others. Some examples of metabolic disorders include cystic fibrosis, hyperlipidemia, gout and rickets.

With more than 25 years of experience in metabolic and endocrine drug discovery and development, Ricerca’s professional staff provides primary- through tertiary- level in vivo and in vitro models that fulfill the needs of pharmaceutical and biotechnology companies at all stages of discovery.

Heading our metabolic-endocrine team are directors with extensive industry experience who have authored numerous peer-reviewed published articles. All have significant experience in preclinical pharmacology and drug development; many have served as principal scientists and section leaders at major pharmaceutical companies.

Click here to see a list of available metabolic/endocrine assays.

Supporting services

• Histology

• Histopathology

• Biomarker – immunohistochemistry

• Screening and profiling assays

• ImmunoSignal™ – mediator release analysis

• OncoPanel™ – anti-cancer profiling and screening

• Early safety screening – cellular toxicity

• ADME/DMPK services