DMPK Overview

Time is at a premium in today’s drug development world, which is why Ricerca's fast-turnaround in vitro and in vivo metabolism services quickly provide the ADME, pharmacokinetic and metabolism profiling data you need to prepare an IND submission and support full development of drug candidates.

We perform routine and non-routine, radiolabeled and non-labeled studies and combine them with powerful new technologies to rapidly identify the most promising compounds from a candidate group. Customized in vivo studies determine your development compound's pharmacokinetic parameters in animals, including metabolite profiling, disposition across tissues and organs and structural identification of metabolites. In support of your study, Ricerca also provides on-site radiolabel synthesis of your drug candidate.

A broad range of on-site analytical expertise and services, such as metabolite standards synthesis, mean you'll be able to choose better development candidates, select them more quickly and evaluate them more fully.