Agrochemical Chemistry

Ricerca provides a full array of chemistry services including analytical and process chemistry, engineering and API manufacturing to meet your needs from discovery to commercial launch. Our experienced chemical development team has a proven track record for excellence in the development, scale-up and manufacturing of small molecule drugs, and our modern 260,000-square-foot complex in Concord, Ohio, includes kilo labs and a pilot plant for flexible manufacturing capacities from 22 to 3,000 liters.

 

A single-source solution for your chemical development needs, all services are provided with the highest quality standards and full regulatory support.

 

Ricerca's chemical development capabilities include:

 

Product Chemistry

  • Product chemistry packages (active ingredient, formulation)

  • Methods development and validation

  • GLP characterization test, control and reference substances

  • Certificate of Analysis (FIFRA, TSCA, OECD and J-MAFF Requirements)

Analytical Chemistry

  • GLP characterization of test and reference materials

  • Analytical method development

  • Independent laboratory validation

  • Comprehensive product chemistry in conformance with regulatory guidelines as established by EEC, JMAFF and USEPA OPPTS

  • 5-batch analysis

  • Impurity determinations

  • Stability studies

Radiolabel Synthesis

  • Non-GMP and cGMP radiosynthesis

  • Gas transfer manifold for isotopic labeling using volatile radiochemicals (14CO2, 14CH3I, 14C phosgene, etc.)

  • GLP characterization with certificate of analysis

  • Stable, isotope-labeled synthesis

  • Dilutions of isotopically labeled compounds

  • Small scale 14C polymer synthesis

Synthetic Chemistry

  • Analytical standards, model compounds and metabolites

Process Services

  • Material preps

    • (Grams to kgs to metric tons)

    • Product candidates

    • Intermediates

  • Process discovery, development and optimization

Custom Manufacturing

At Ricerca, we conduct custom manufacturing in kilo labs and in our own pilot plant to produce materials for our agrochemical clients. Ricerca has demonstrated expertise in complex, multi-step synthesis including:

  • Small-volume preparation of active materials in kilo lab quantities

  • Large-scale preparation of intermediates in pilot plant

  • Synthesis of metabolites

  • Synthesis of standards