About Ricerca Biosciences

Founded in 1986, Ricerca Biosciences offers a comprehensive suite of non-clinical discovery support and integrated R&D services to support drug candidate development from lead identification through IND and NDA submission.  Biological capabilities include early pharmacokinetic and metabolism screening, pilot toxicology evaluations, IND/NDA-enabling toxicology and DMPK development of both small molecules and biologics.  Supporting the chemical development needs, Ricerca offers synthetic, medicinal and process chemistry, radiochemistry, and cGMP API manufacturing of small scale clinical batches through commercial API production, with complete analytical drug substance and drug product characterization.

 

Ricerca’s new Senior Management Team is revitalizing our scientific platforms, renewing existing partnerships and developing new client relationships.  Our experienced scientists deliver world-class expertise and services to help shorten time to IND and bring molecules to the clinic faster.  We have the capacity and integrated scientific capabilities, on a single research site in Concord, Ohio, to deliver any size project. For the shortest and highest value based development program, from compound lead selection to regulatory filing, contact Ricerca. Ricerca also has Drug Safety Assessment operations in Lyon, France, offering a full spectrum of non-clinical services supporting drug product development from pre-clinical through market submission and tailored service to their customers.

 

 

Discovery DMPK and Toxicology Support

  • Custom synthesis and molecule design
  • In Vitro DMPK screening
  • Early toxicology and PK screening
  • In Vivo safety models
  • In Vivo DMPK, ADME & metabolite profiling

Chemical Development

  • Analytical chemistry
  • Synthetic and Process chemistry
  • Engineering and scale-up
  • Radiosynthesis
  • API production with cGMP controls, preclinical to commercial scale

Drug Safety and Metabolism

  • General toxicology/TK
  • Safety pharmacology
  • Oral, Parental and Continuous infusion
  • IND-enabling Integrated DSM Support
  • Chronic toxicology & carcinogenicity
  • Juvenile toxicology
  • DART
  • Bioanalytical services